In vitro ACTIVITY OF RO363, A β1-ADRENOCEPTOR SELECTIVE AGONIST
نویسندگان
چکیده
منابع مشابه
Synthesis and in Vitro and in Vivo Characterization of Highly β1-Selective β-Adrenoceptor Partial Agonists
β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β1-selective molecules exist. To address this clinical need, we re-evaluated LK 204-545 (1), (1) a selective β1-adrenoceptor antagonist, and discovere...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1980
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1980.tb10860.x